CARTR Annual report – 2011

Assisted reproductive technologies (ART) in Canada: 2011 results from the Canadian ART Register

Joanne Gunby, M.Sc.
CARTR Co-ordinator

Abstract

In 2011, 31 of 32 Canadian assisted reproductive technology (ART) clinics participated in the Canadian ART Register (CARTR). A total of 23,997 cycles was reported to CARTR, resulting in 7030 clinical pregnancies and at least 5329 deliveries, 5276 live births, 4253 singleton live births, 3317 healthy term singletons, 1030 multiple births (including 21 high-order multiple births), and 6381 infants, 33% of whom were from multiple gestations. Birth outcomes were unknown for 251 ongoing pregnancies (4.5%).

In 14,866 IVF/ICSI cycles using the woman’s own oocytes, per cycle started, the clinical pregnancy rate was 31.0% (37.6% per embryo transfer), the live birth rate was 23.9%, the singleton live birth rate was 19.0%, and the healthy term singleton rate was 14.7%; the multiple birth rate per delivery was 20.5%, with a high-order multiple birth rate of 0.5%. ICSI was performed in 71% of cycles. One embryo was transferred in 36% of cycles and one or two embryos in 84% of cycles. In 647 IVF/ICSI cycles using donor oocytes, per cycle started, the clinical pregnancy rate was 45.7%, the live birth rate was 37.7%, the singleton live birth rate was 30.4%, and the healthy term singleton rate was 24.5%; the multiple birth rate was 19.6%, with no high-order multiple birth. In 5886 FET cycles using the woman’s own oocytes, per cycle started, the clinical pregnancy rate was 27.1%, the live birth rate was 19.1%, the singleton live birth rate was 15.9%, and the healthy term singleton rate was 12.7%; the multiple birth rate was 16.8%, with a high-order multiple birth rate of 0.4%.

The number of ART cycles performed in Canada increased by 30% in 2011 compared with the previous year. In IVF/ICSI cycles, the multiple birth rate was reduced by 3.3 percentage points compared with 2010; in consequence, the clinical pregnancy and live birth rates were also lower. In donor oocyte and FET cycles, the multiple birth rates were also lower than in 2010, while the clinical pregnancy and live birth rates remained about the same.
Full article is available: CARTR 2011