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CARTR Annual report – 2012

Assisted reproductive technologies (ART) in Canada: 2012 results from the Canadian ART Register

Joanne Gunby, M.Sc.
CARTR Co-ordinator

Abstract

In 2012, 32 of 33 Canadian assisted reproductive technology (ART) clinics participated in the Canadian ART Register (CARTR). A total of 27,356 cycles was reported to CARTR, resulting in 8096 clinical pregnancies and at least 6017 deliveries, 5971 live births, 5031 singleton live births, 3921 healthy term singletons, 945 multiple births (including 26 triplet births), and 6988 infants, 27% of whom were from multiple gestations. Birth outcomes were unknown for 462 ongoing pregnancies (7.1%).

In 16,062 IVF/ICSI cycles using the woman’s own oocytes, per cycle started, the clinical pregnancy rate was 31.1% (38.8% per embryo transfer), the live birth rate was 23.5%, the singleton live birth rate was 19.6%, and the healthy term singleton rate was 15.3%; the multiple birth rate per delivery was 16.5%, with a triplet birth rate of 0.45%. ICSI was performed in 70% of cycles. One embryo was transferred in 44% of cycles and one or two embryos in 88% of cycles. In 617 IVF/ICSI cycles using donor oocytes, per cycle started, the clinical pregnancy rate was 45.1%, the live birth rate was 35.7%, the singleton live birth rate was 29.2%, and the healthy term singleton rate was 20.4%; the multiple birth rate was 18.4%, with only one triplet birth (0.46%). In 7466 FET cycles using the woman’s own oocytes, per cycle started, the clinical pregnancy rate was 29.9%, the live birth rate was 22.1%, the singleton live birth rate was 18.8%, and the healthy term singleton rate was 14.8%; the multiple birth rate was 15.1%, with a triplet birth rate of 0.37%.

The number of ART cycles performed in Canada increased by 14% in 2012 compared with the previous year. In IVF/ICSI cycles, the multiple birth rate was reduced by 4 percentage points compared with 2011, with little change in the clinical pregnancy and live birth rates. In donor oocyte and FET cycles, the multiple birth rates were similar to those of 2011, while the clinical pregnancy and live birth rates stayed about the same in donor oocyte cycles and increased in FET cycles.
Full article is available: CARTR 2012